Cefotaxime (sodium salt)

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Cat No: 16040

Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-pr...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(6R)-3-[(acetyloxy)methyl]-7R-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt

Correlated keywords:

63527-52-6 antibiotics cephalosporin gram-negative gram-positive bacteria ?-lactamase sodium salts in vitro potent grams negative positive streptococcal species S. aureus penicillin-resistant penicillin resistant S. pneumonia beta-lactamase b-lactamase .beta.-lactamase b ? beta .beta. lactamase baxim bilog biotax bioxim calcef califrid cefso cefacron cefantral cefcan cefomed cefomerc cefomerk cefon cefotam cefotax ccefoxim cefronate ceftim ceftop ceftoringe chemcef clafora claftax clavox eaxiron elkotak epotazime evotaxime excef forax fortax HR 756 HR756 HR-756 novatax oritaxim pretor RUs 24756 RU24756 RU-24756 sefagen tolycar zafixime

Product Overview:
Cefotaxime is a cephalosporin antibiotic with potent in vitro activity against streptococcal species, including S. aureus (IC50 = 2 µg/ml) and penicillin-resistant S. pneumoniae.{25856} It is also effective against a wide range of other β-lactamase-producing bacterial species (MIC90s = 0.01 - 130 µg/ml).{25856} Cefotaxime acts by interfering with bacterial cell wall synthesis and has also been shown to be a competitive inhibitor of β-lactamase.{25971}

Size	250 mg
Shipping	dry ice
CAS Number	64485-93-4
Molecular Formula	C₁₆H₁₆N₅O₇S₂ • Na
SMILES	[H][C@@]1([C@@H]2NC(/C(C3=CSC(N)=N3)=N\OC)=O)N(C(C([O-])=O)=C(COC(C)=O)CS1)C2=O.[Na+]
Molecular Weight	477,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.