Cefazolin (sodium salt)

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Cat No: 15776

Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabili...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(6R)-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-7R-[[2-(1H-tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt

Correlated keywords:

25953-19-9 25747-?35-?7 29876-?03-?7 Antibiotics anti-biotics anti biotics cephalosporin immune suppression immunosuppressant Gram-positive Gram-negative bacteria inhibitors inhibits inhibitions bacterial cells walls synthesis Grams positive negative infectious diseases broad-spectrum broad spectrum in vitro cefacidal cefamezin cefrina faxilen kefol kefazol novaporin reflin zinol Zolicef acef atirin azolin biazolina bor-cefazol DC sodium salts firmacef Iespor lampocef liviclina NSCs 291561 NSC291561 NSC-291561 SKFs 41558 SKF41558 SKF-41558 Ancef biazolina elzogram gramazin kefzolan kezolin Staphylococcus Escheria Proteus Klebsiella

Product Overview:
Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml).{25759} It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively). Formulations containing cefazolin have been used to treat a variety of bacterial infections.

Size	100 mg
Shipping	dry ice
CAS Number	27164-46-1
Molecular Formula	C₁₄H₁₃N₈O₄S₃ • Na
SMILES	O=C(CN1N=NN=C1)N[C@H](C2=O)[C@]3([H])N2C(C([O-])=O)=C(CSC4=NN=C(C)S4)CS3.[Na+]
Molecular Weight	476,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2918.99
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.