SCH 23390 (hydrochloride)

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Cat No: 15631

Biochemicals - Receptor Pharmacology

SCH 23390 is a halobenzazepine that acts as a selective antagonist of the dopamine D1-like receptor subtypes D1 and D5 (Kis = 0.2 and 0.3 nM, respectively).{25563} In vivo studies have demonstrated that SCH 23390 can abolish pharmacologically-induced ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

8-chloro-2,3,4,5-tetrahydro-3-methyl-5R-phenyl-1H-3-benzazepin-7-ol, monohydrochloride

Correlated keywords:

halobenzazepine antagonists dopamines D1-like receptors D1 D5 seizures neurological disorders neurosciences HCl selective SCH23390 SCH-23390 SCHs 23390 in vivo brain functions likes biochemistry (R)-(+)-Sch R(+)-SCH-23390 R(+)-SCH23390 (R)-(+)-Sch23390 (R)-(+)-Sch-23390 (R)-(+)-Sch

Product Overview:
SCH 23390 is a halobenzazepine that acts as a selective antagonist of the dopamine D1-like receptor subtypes D1 and D5 (Kis = 0.2 and 0.3 nM, respectively).{25563} In vivo studies have demonstrated that SCH 23390 can abolish pharmacologically-induced seizures.{25563} This compound is useful for studying the role of the dopamine system in normal brain function and neurological disorders.{24104,17607,11498,20951}

Size	10 mg
Shipping	dry ice
CAS Number	125941-87-9
Molecular Formula	C₁₇H₁₈ClNO • HCl
SMILES	CN1C[C@H](C2=CC=CC=C2)C3=C(C=C(Cl)C(O)=C3)CC1.Cl
Molecular Weight	324,2
Formulation	A crystalline solid
Purity	≥99%
Custom Code	2903.99
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.