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GLP-1 (7-36) amide (trifluoroacetate salt)

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    GLP-1 (7-36) amide (trifluoro<wbr/>acetate salt)
  • GLP-1 (7-36) amide (trifluoro<wbr/>acetate salt)
Cat No: 15069
Biochemicals - Peptides
Cayman

GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and displays various antidiabetic effects by potentiating glucose-induced secretion of insuli...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Correlated keywords:
  • 107444-51-9 113789-12-1 873133-88-1 GLP-1 GLP1 GLPs 1 one peptides hormones intestinal L-cells L cells receptors GLP1R 1R GLP-1R pancreas antidiabetics anti diabetics anti-diabetics types two 2 diabetes glucose insulin pancreatic ?-cells glucagon likes peptides peptide-1 amides hormones intestinal nutrients nutrition inhibiting inhibits inhibitors b-cell apoptosis beta-cells .beta.-cells ?-cells neogenesis secretions gastric satiety peripheral disposals agonists MKCs 253 MKC253 MKC-253 signals transduction metabolism metabolic syndromes endocrinology diabetes3
Product Overview:
GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and displays various antidiabetic effects by potentiating glucose-induced secretion of insulin from pancreatic β-cells, increasing insulin expression, inhibiting β-cell apoptosis, promoting β-cell neogenesis, reducing glucagon secretion, delaying gastric emptying, promoting satiety, and increasing peripheral glucose disposal.{24256}
Size 500 µg
Shipping dry ice
SMILES O=C([C@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](NC([C@@]([H])(NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(C=C4)O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]([H])(NC([C@H](CC5=CC=C
Molecular Weight 3297,6
Formulation A crystalline solid
Custom Code 3504.00
UNSPSC code 12352204

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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