4-DAMP

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4-DAMP

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Cat No: 14574

Biochemicals - Receptor Pharmacology

4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4-[(2,2-diphenylacetyl)oxy]-1,1-dimethyl-piperidinium, monoiodide

Correlated keywords:

81405-11-0 receptors antagonists neurosciences 4DAMP 4 DAMPs potent muscarinic M3 M-3 Ms 3 regulations regulates functions high affinity M5 M-5 5 methiodides

Product Overview:
4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}

Size	25 mg
Shipping	room temp.
CAS Number	1952-15-4
Molecular Formula	C₂₁H₂₆NO₂ • I
SMILES	O=C(OC1CC[N+](C)(C)CC1)C(C2=CC=CC=C2)C3=CC=CC=C3.[I-]
Molecular Weight	451,3
Formulation	A solid
Purity	≥98%
Custom Code	2933.49
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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