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JWH 203 N-(4-hydroxypentyl) metabolite-d5

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    JWH 203 N-<wbr/>(4-<wbr/>hydroxypentyl) metabolite-<wbr/>d<sub>5</sub>
  • JWH 203 N-<wbr/>(4-<wbr/>hydroxypentyl) metabolite-<wbr/>d<sub>5</sub>
Cat No: 14367
Biochemicals - Isotopically Labeled Standards
Cayman

JWH 203 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4 ,5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 203 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry....

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Territorial Availability: Available through Bertin Technologies only in France
Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
Special Advice: Please check regulation status before ordering; additionel fees can apply.
Synonyms:
  • 2-(2-chlorophenyl)-1-(1-(4-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)ethan-1-one
Correlated keywords:
  • cannabinoids receptors JWHs 250 CB1 CB2 cannabimimetics forensics pains metabolites CBs JWH-250 JWH250 203 JWH203 JWH-203 metabolisms serum urine phase I hydroxylated hydroxypentyl neurosciences forensics analgesics chemicals phenylacetylindole agonists synthetics central peripheral 13634 phenylacetyl naphthoyl rings aminoalkylindoles potent binding binds activity physiological research applications LC-MS LC/MS GC-MS GC/MS mass spectrometry MS analytical references standards
Product Overview:
JWH 203 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4 ,5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 203 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 203 (Item No. 9000736) is an analgesic chemical from the phenylacetylindole family that acts as an agonist with Ki values of 8.0 and 7.0 nM at the central cannabinoid (CB1) and peripheral (CB2) receptors, respectively.{17655} Similar to the related 2'-methoxy compound JWH 250 (Item No. 13634), JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 receptors (JWH 250 Kis = 11 and 33 nM, respectively).{17655} JWH 203 N-(4-hydroxypentyl) metabolite is expected to be a metabolite of JWH 203 that would be detectable both in serum and in urine. While similar hydroxylated phase I metabolites of synthetic CBs retain activity, the physiological properties of this compound have yet to be determined.{20952,20953} This product is intended for research and forensic applications.
Size 1 mg
Shipping dry ice
CAS Number 2747915-98-4
Molecular Formula C21H17D5ClNO2
SMILES O=C(CC1=C(Cl)C=CC=C1)C2=C([2H])N(CCCC(O)C)C3=C2C([2H])=C([2H])C([2H])=C3[2H]
Molecular Weight 360,9
Formulation A solution in methyl acetate
Purity ≥99% deuterated forms (d1-d5)
Custom Code 3822.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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