Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

Fludarabine Phosphate

  • Zoom
    Fludarabine Phosphate
  • Fludarabine Phosphate
Cat No: 14251
Cayman

Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cell...

More

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 2-fluoro-9-(5-O-phosphono-?-D-arabinofuranosyl)-9H-purin-6-amine
Correlated keywords:
  • fludara fludura NSC312887 NSC328002 LX1 FAMP arabinoside 3',5'-monophosphate 9bd anti-proliferative RPMI8226 LI-210 P-388 BCL2 BCL-2 BH3 IAP3 IAP-3 BIRC4 BIRC-4 anticancer
Product Overview:
Fludarabine phosphate is an injectable form of fludarabine (Item No. 14128).{22565} Fludarabine is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that disrupts ribonucleotide reductase and DNA polymerase in blood cells. It exhibits antiproliferative activity (IC50 = 1.54 μM in an RPMI-8226 myeloma cell line) and triggers apoptosis by increasing Bax and decreasing Bid, XIAP, and survivin expression.{22556,22553} Fludarabine is effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anti-cancer activity against human hematological malignancies in vivo.{22565,22552,22557}
Size 5 mg
Shipping dry ice
CAS Number 75607-67-9
Molecular Formula C10H13FN5O7P
SMILES OP(OC[C@@H]1[C@@H](O)[C@H](O)[C@H](N2C=NC3=C2N=C(F)N=C3N)O1)(O)=O
Molecular Weight 365,2
Formulation A crystalline solid
Purity ≥95%
Custom Code 2933.49
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Fludarabine Phosphate There are 8 products.

Search