L-Thyroxine

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L-Thyroxine

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Cat No: 14116

Biochemicals - More Biochemicals

L-Thyroxine is a synthetic form of the thyroid hormone thyroxine.{43116,43117,43118} In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone (Item No. 22917) from the anterior pituit...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine

Correlated keywords:

74-16-8 587-29-1 587-30-4 7200-84-2 7488-70-2 1373931-44-2 L-thyroxin thyroxin levotiron NSC36397 NSC-36397 tetraiodothyronine thyroxinal thyrax T4 synthetic thyroid hormones physiological vertebrates hypothyroidism henning sk&f 1-6528 thyreoideum

Product Overview:
L-Thyroxine is a synthetic form of the thyroid hormone thyroxine.{43116,43117,43118} In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone (Item No. 22917) from the anterior pituitary in mice.{43116} It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse model of hypothyroidism.{43117,43118} Formulations containing L-thyroxine have been used in the treatment of hypothyroidism.

Size	500 mg
Shipping	dry ice
CAS Number	51-48-9
Molecular Formula	C₁₅H₁₁I₄NO₄
SMILES	OC1=C(I)C=C(OC2=C(I)C=C(C[C@H](N)C(O)=O)C=C2I)C=C1I
Molecular Weight	776,9
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2903.99
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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