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Prostaglandin F2?-1-glyceryl ester-d5

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    Prostaglandin F<sub>2?</sub>-<wbr/>1-<wbr/>glyceryl ester-<wbr/>d<sub>5</sub>
  • Prostaglandin F<sub>2?</sub>-<wbr/>1-<wbr/>glyceryl ester-<wbr/>d<sub>5</sub>
Cat No: 13883
Biochemicals - Isotopically Labeled Standards
Cayman

Prostaglandin F2α-1-glyceryl ester-d5 (PGF2α-1-glyceryl ester-d5) contains five deuterium atoms. It is intended for use as an internal standard for the quantification of PGF2α-1-glyceryl ester by GC- or LC-MS. 2-Arachidonoyl glycerol (2-AG) has been i...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 9?,11?,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester-d5
Correlated keywords:
  • standards deuterium internal isotopes GC/MS GC-MS LC/MS LC-MS mass spectrometry deuterated Prostaglandins PGF2alpha-1-GE PGF2.alpha.-1-GE esters 2-AG 2-arachidonoyl-glycerol COX-2 metabolites cyclooxygenases PGHS-2 synthases PGHS2 COX2 PGF2alpha-2-GE PGF2.alpha.-2-GE PGFa-2-GE PGF2a-1-GE cannabinoids cbs synthetic Prostaglandins PGF2alpha-1-GE
Product Overview:
Prostaglandin F2α-1-glyceryl ester-d5 (PGF2α-1-glyceryl ester-d5) contains five deuterium atoms. It is intended for use as an internal standard for the quantification of PGF2α-1-glyceryl ester by GC- or LC-MS. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase 2 and specific PGH2 isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.{10555}
Size 25 µg
Shipping dry ice
Molecular Formula C23H35D5O7
SMILES O[C@@H]1[C@H](C/C=C\CCCC(OC([2H])([2H])C(O)([2H])C([2H])([2H])O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
Molecular Weight 433,6
Formulation A solution in acetonitrile
Purity ≥99% deuterated forms (d1-d5); ?1% d0
Custom Code 2937.50
UNSPSC code 12352100

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Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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