Farnesyl Alcohol

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Farnesyl Alcohol

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Cat No: 13268

Biochemicals - Lipids

Farnesyl alcohol is an isoprenoid originally isolated from plants but also produced in mammals, including humans, as an intermediate in the mevalonate biosynthesis pathway.{39250} It acts as an agonist at the peroxisome proliferator-activated receptor...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3,7,11-trimethyl-2,6,10-dodecatrien-1-ol

Correlated keywords:

isoprenoid anti-cancer candida farnesylalcohol nikkosome NSC60597 FCI119a 106-28-5

Product Overview:
Farnesyl alcohol is an isoprenoid originally isolated from plants but also produced in mammals, including humans, as an intermediate in the mevalonate biosynthesis pathway.{39250} It acts as an agonist at the peroxisome proliferator-activated receptors PPARα and PPARγ (ED50s = 5.5 and 28 µM, respectively).{39249} Farnesyl alcohol has broad anticancer properties in vitro and in xenograft mouse models, inhibiting proliferation, slowing tumor growth, and inducing apoptosis.{39246,39245,39247} In addition, it acts as a quorum sensing molecule in fungi, including C. albicans, where it reduces virulence by blocking the transition from yeast to mycelium.{39244,39248}

Size	5 g
Shipping	dry ice
CAS Number	4602-84-0
Molecular Formula	C₁₅H₂₆O
SMILES	OC/C=C(CC/C=C(CC/C=C(C)\C)\C)\C
Molecular Weight	222,4
Formulation	A neat oil
Purity	≥98% (mixture of isomers)
Custom Code	2916.31
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.