Pterostilbene

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Pterostilbene

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Cat No: 13000

Biochemicals - Lipids

Pterostilbene is a polyketide synthase-derived stilbene originally isolated from P. santalinus that has diverse biological activities.{62166,17408,17413,17411,60517} It reduces photooxidative leakage induced by the herbicide acifluorfen in C. sativus ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-phenol

Correlated keywords:

Pterocarpus Cucumis Hep G2 2647 P 1499 P1499

Product Overview:
Pterostilbene is a polyketide synthase-derived stilbene originally isolated from P. santalinus that has diverse biological activities.{62166,17408,17413,17411,60517} It reduces photooxidative leakage induced by the herbicide acifluorfen in C. sativus cotyledon disks when used at a concentration of 30 µg/ml.{17408} Pterostilbene (25 and 50 µM) inhibits invasion and migration of HepG2 hepatoma cells induced by 12-O-tetradecanoylphorbol 13-acetate (TPA; Item No. 10008014).{17413} It inhibits the production of nitric oxide (NO) and prostaglandin E2 (PGE2; Item No. 14010) in LPS-stimulated RAW 264.7 macrophages when used at concentrations of 10 and 20 µM.{17411} Pterostilbene (100 and 300 µM) activates peroxisome proliferator-activated receptor α (PPARα) in H4IIEC3 rat hepatoma cells.{60517} It decreases plasma glucose and LDL levels and increases plasma levels of HDL in a hamster model of hypercholesterolemia induced by a high-fat diet when administered in the diet at 25 ppm.

Size	50 mg
Shipping	dry ice
CAS Number	537-42-8
Molecular Formula	C₁₆H₁₆O₃
SMILES	COc1cc(/C=C\c2ccc(O)cc2)cc(OC)c1
Molecular Weight	256,3
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2907.19
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.