25-hydroxy Vitamin D2

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25-hydroxy Vitamin D₂

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Cat No: 12078

Biochemicals - Natural Products

25-hydroxy Vitamin D2 is a metabolite of vitamin D2 (Item No. 11791).{57807} It is formed from vitamin D2 by the cytochrome P450 (CYP) isoforms CYP2R1 and CYP27A1, which have 25-hydroxylase activity, and is bound to vitamin D binding protein (DBP) and...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-cyclohexanol

Correlated keywords:

21343-34-0 29864-49-1 50351-34-3 P 450 CYP 450 CYP 2R1 27A1 24A1 27B1

Product Overview:
25-hydroxy Vitamin D2 is a metabolite of vitamin D2 (Item No. 11791).{57807} It is formed from vitamin D2 by the cytochrome P450 (CYP) isoforms CYP2R1 and CYP27A1, which have 25-hydroxylase activity, and is bound to vitamin D binding protein (DBP) and albumin in the liver, then secreted into the bloodstream.{60080} 25-hydroxy Vitamin D2 is transported to the kidney, where it is preferentially 24-hydroxylated by CYP24A1 to produce 24,25-dihydroxy vitamin D2.{60080} It can also be hydroxylated by CYP27B1 to produce 1,25-dihydroxy vitamin D2.{60080,57807} Serum levels of 25-hydroxy vitamin D2 have been used as a marker of vitamin D status.{57808}

Size	500 µg
Shipping	dry ice
CAS Number	21343-40-8
Molecular Formula	C₂₈H₄₄O₂
SMILES	C=C1CC[C@H](O)C/C1=C\C=C2CCC[C@@]3(C)[C@@]\2([H])CC[C@]3([H])[C@H](C)/C=C/[C@H](C)C(C)(O)C
Molecular Weight	412,7
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2936.29
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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