Salsalate

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Salsalate

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Cat No: 11911

Biochemicals - More Biochemicals

Salsalate is a non-steroidal anti-inflammatory drug (NSAID) and prodrug form of salicylic acid.{49749} It is converted to salicylic acid by hydrolysis. It inhibits prostaglandin E2 (PGE2; Item No. 14010) production in isolated human whole blood stimul...

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Territorial Availability: Available through Bertin Technologies only in France

                                            Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
                    

Special Advice: Dangerous Good in said quantity, not available for sale.

Synonyms:

2-hydroxy-2-carboxyphenyl ester-benzoic acid

Correlated keywords:

diacesal diplosal disalgesic disalicylic acid disalyl mono-gesic salical salicyl salicylate salicyloxysalicylic salicyloylsalicylic salicylsalicylic salysal sasapyrine sasapyrinum nonacetylated salicylate sodium salicylate acetylsalicylate aspirin NSAID insulin resistance type 2 rheumatic pain arthritis non-acetylated Disalcid NSC49171 salflex salina sasapirin

Product Overview:
Salsalate is a non-steroidal anti-inflammatory drug (NSAID) and prodrug form of salicylic acid.{49749} It is converted to salicylic acid by hydrolysis. It inhibits prostaglandin E2 (PGE2; Item No. 14010) production in isolated human whole blood stimulated with LPS (IC50 = 39.9 µM).{32442} Salsalate (1,000 mg/kg) inhibits weight gain and decreases fasting plasma glucose and insulin levels, as well as decreases plasma cholesterol and triglyceride levels in a mouse model of non-alcoholic steatohepatitis (NASH) induced by a high-fat high-cholesterol diet.{49750} Formulations containing salsalate have been used in the treatment of pain associated with osteoarthritis and rheumatoid arthritis.

Size	100 g
Shipping	dry ice
CAS Number	552-94-3
Molecular Formula	C₁₄H₁₀O₅
SMILES	OC1=CC=CC=C1C(OC2=C(C(O)=O)C=CC=C2)=O
Molecular Weight	258,2
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2907.19
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.