Sesamolin

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Sesamolin

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Cat No: 11754

Biochemicals - Natural Products

Sesamolin is a lignin found in S. indicum with diverse biological activities. It reduces lipid peroxidation in rat liver and kidneys in vivo but has no effect on lipid peroxidation activity of rat liver microsomes in vitro.{36103} In vivo, sesamolin r...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole

Correlated keywords:

schistosoma FFA BV2 Molt4B ferroptosis

Product Overview:
Sesamolin is a lignin found in S. indicum with diverse biological activities. It reduces lipid peroxidation in rat liver and kidneys in vivo but has no effect on lipid peroxidation activity of rat liver microsomes in vitro.{36103} In vivo, sesamolin reduces epididymal white adipose tissue weight and serum triacylglcerol, free fatty acid, phospholipid, and cholesterol concentrations in rats.{360103} Sesamolin inhibits growth of Molt-4B human lymphoid leukemia cells via induction of apoptosis in a dose-dependent manner.{360105} It also reduces hypoxia-induced lactate hydrogenase (LDH) release and dichlorofluorescin-sensitive reactive oxygen species (ROS) production in BV-2 microglia grown under hypoxic conditions.{360106}

Size	1 mg
Shipping	dry ice
CAS Number	526-07-8
Molecular Formula	C₂₀H₁₈O₇
SMILES	[H][C@]1(CO2)[C@@](CO[C@@H]1C3=CC=C(OCO4)C4=C3)([H])[C@H]2OC5=CC=C6C(OCO6)=C5
Molecular Weight	370,4
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.99
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.