Alizarin

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Alizarin

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Cat No: 11676

Biochemicals - Small Molecule Inhibitors

Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively).{22084} Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

1,2-dihydroxy-9,10-anthracenedione

Correlated keywords:

1328-02-5 84754-86-9 anthraquinone NSC7212 metachrome mordant alizarina alizarine-3B L paste blueish lake 2P 3P IPX NAC B2 IP IPP C.I. certiqual orange number 15 deep crimson madder 10821 eljon mitsui 11 qiansu CYP1-A1 A2 B1 anthraquinonediol turkey CYP450 CYP-450 anti-oxidant CI58000

Product Overview:
Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively).{22084} Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes.{34371} It also reduces hepatic content of thiobarbituric acid-reactive substances and serum levels of alanine aminotransferase in poisoned rats.{34371} Alizarin is also used as a red dye to stain bacteria, human adipose-derived stem cells, multipotent adult progenitor cells, skin, hair, and keratin fibers.{22804,34372,34370}

Size	50 g
Shipping	room temp.
CAS Number	72-48-0
Molecular Formula	C₁₄H₈O₄
SMILES	O=C1C2=C(C(O)=C(O)C=C2)C(C3=C1C=CC=C3)=O
Molecular Weight	240,2
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2907.29
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.