Alternariol

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Alternariol

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Cat No: 11306

Biochemicals - Toxins

Alternariol is a mycotoxin, a toxic secondary fungal metabolite, produced by Alternaria molds. It is cytotoxic, fetotoxic, teratogenic, mutagenic, and genotoxic.{20385} It induces cytochrome P450 1A1 expression and apoptosis in mouse hepatoma cells (2...

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Territorial Availability: Available through Bertin Technologies only in France

                                            Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
                    

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Synonyms:

3,7,9-trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one

Correlated keywords:

11003-13-7 fungus molds mycotoxins toxins metabolites Alternaria CYP450 cytochromes P450 1A1 cytotoxin fetotoxin teratogenic mutagenic genotoxin apoptosis hepatoma cells 641-38-3 AC1NSEOY A1312 ZINC00402623 NSC-638263 NSC638263 CCRIS6734 CCRIS-6734 NCGC00180653-01 LS61189 LS-61189 LS 61189 NP001789 NP-001789 NP 001789 C16838 C-16838 C 16838 5-18-04-00516 BRD-K62196712-001-01-3

Product Overview:
Alternariol is a mycotoxin, a toxic secondary fungal metabolite, produced by Alternaria molds. It is cytotoxic, fetotoxic, teratogenic, mutagenic, and genotoxic.{20385} It induces cytochrome P450 1A1 expression and apoptosis in mouse hepatoma cells (20-40 μM).{20386} Alternariol, whose synthesis is inhibited by light, naturally occurs on fruits, vegetables, and cereals, such as apples, tomatoes, and wheat.{20387}

Size	1 mg
Shipping	dry ice
CAS Number	641-38-3
Molecular Formula	C₁₄H₁₀O₅
SMILES	CC1=C(C2=C(C(O3)=O)C(O)=CC(O)=C2)C3=CC(O)=C1
Molecular Weight	258,2
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2907.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.