Lupeol

Confirm delete?

Lupeol

Zoom

Cat No: 11215

Lupeol, a dietary triterpene found in certain fruits, vegetables, and medicinal plants, has potent anti-inflammatory, anticarcinogenic, antimutagenic, and antimalarial activity. It suppresses the growth of hepatocellular carcinoma cell lines SMMC7721 ...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3?)-lup-20(29)-en-3-ol

Correlated keywords:

AC-1371 AC1371 AC 1371 132473-92-8 200123-55-3 fagarsterol dietary triterpenes anti-inflammatory anticarcinogenic antimutagenic antimaralia fruits vegetables medicinal plants antimalarial cells carcinoma cancers SMMC7721 SMMC-7721 SMMC 7721 HepG2 melanoma mel928 mel-928 mel 928 mel1241 mel-1241 mel 1241 blood pressure strokes hypertension rats genes cholesterol synthesis neutrophils monogynol B NSC-90487 NSC90487 beta-viscol b-viscol

Product Overview:
Lupeol, a dietary triterpene found in certain fruits, vegetables, and medicinal plants, has potent anti-inflammatory, anticarcinogenic, antimutagenic, and antimalarial activity. It suppresses the growth of hepatocellular carcinoma cell lines SMMC7721 and HepG2 with IC50 values of 45 and 48.5 μM and melanoma cell lines Mel 928 and Mel 1241 with IC50 values of 75 and 72 μM.{20463,20465} At 0.76 g/kg lupeol causes a significant decrease in the blood pressure of stroke-prone hypertensive rats and reduces expression of hepatic genes involved in triglyceride and cholesterol synthesis.{20464} It also has significant anti-inflammatory effects at 50 mg/kg in a carrageenan-induced edema model, inhibiting neutrophil migration.{20466}

Size	5 mg
Shipping	dry ice
CAS Number	545-47-1
Molecular Formula	C₃₀H₅₀O
SMILES	O[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC[C@@]4([H])[C@@]3(C)CC[C@]5(C)[C@]4([H])[C@H](C(C)=C)CC5)([H])C1(C)C
Molecular Weight	426,7
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2907.19
UNSPSC code	12352100

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.