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Diphenhydramine (hydrochloride)

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    Diphen<wbr/>hydramine (hydro<wbr>chloride)
  • Diphen<wbr/>hydramine (hydro<wbr>chloride)
Cat No: 11158
Biochemicals - Receptor Pharmacology
Cayman
€33.00
Price is excluding VAT and does not include packaging neither shipping

Diphenhydramine (DPH) is a first generation antihistamine that is a potent antagonist of the histamine H1 receptor (Ki = 11.7 nM using human recombinant receptors).{15199,22787} DPH readily crosses the blood-brain barrier and produces diverse cognitiv...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Synonyms:
  • 2-(diphenylmethoxy)-N,N-dimethyl-ethanamine, monohydrochloride
Correlated keywords:
  • 58-73-1 HCl receptors antagonists immunology neurosciences allergy/asthma asthma allergy allergies histamines muscarinic cholinergic antihistamines humans H1 blood-brain barrier bloods brains diverse cognitive psychomotor effects M1 M2 M3 M4 M5 M-1 M-2 M-3 M-4 M-5 M 1 2 3 4 5 central nervous systems CNS alledryl allergan allergina allergival amidryl asdrin bagodryl bax bena bena-fedrin fedrin benadril HCl Benadryl benison benocten benodine benylin benzantin benzhydramine benzhydrol b-dimethylaminoethyl ether β-dimethylaminoethyl beta-dimethylaminoethyl .beta.-dimethylaminoethyl dimethylaminoethyl denydryl dibondrin diphenhydramine dimedrol dimedrolum diphantine diphenhydramine fenylhist halbmond histacyl noctomin resmin restamin S8 S-8 S 8 sedopretten sekundal D sekundal-D syntedril Theraflu vena wehydryl
Product Overview:
Diphenhydramine (DPH) is a first generation antihistamine that is a potent antagonist of the histamine H1 receptor (Ki = 11.7 nM using human recombinant receptors).{15199,22787} DPH readily crosses the blood-brain barrier and produces diverse cognitive and psychomotor effects.{15199,22788} DPH also antagonizes muscarinic cholinergic receptors (Kis = 100 to 260 nM for M1-M5), increasing the range of central nervous system effects and applications.{22786} This product is also available as an analytical reference standard (Item No. 22489).
Size 100 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 147-24-0
Molecular Formula C17H21NO • HCl
SMILES CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Molecular Weight 291,8
Formulation A crystalline solid
Purity ≥98%
Custom Code 2922.19
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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