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Podoplanin Monoclonal Antibody (Clone NZ-1.2)

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    Podoplanin Monoclonal Antibody (Clone NZ-<wbr/>1.2)
  • Podoplanin Monoclonal Antibody (Clone NZ-<wbr/>1.2)
Cat No: 11004
Antibodies - Monoclonal Antibodies
Cayman
€231.00
Price is excluding VAT and does not include packaging neither shipping

Podoplanin is a mucin type-1 glycoprotein of 40-43. Podoplanin is expressed in many tumors and many normal cells, especially lymphatic epithelial cells and follicular DCs. It appears to serve as a ligand for CLEC-2. Podoplanin expression is positively...

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: 1 ea

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Correlated keywords:
  • mucin glycoproteins T1A gp38 aggrus tumors cells ligands CLEC-2 metastases tissues Th17 CD4+ humans PBMC antibodies
Product Overview:
Podoplanin is a mucin type-1 glycoprotein of 40-43. Podoplanin is expressed in many tumors and many normal cells, especially lymphatic epithelial cells and follicular DCs. It appears to serve as a ligand for CLEC-2. Podoplanin expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue.{19761,19762,19763} It has also been determined that podoplanin expression is induced through Src activation of Cas.{19760} Recently there are indications of podoplanin presence on Th17 cells.{19759} Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC.
Size 1 ea
Shipping dry ice
Stability Store at -20 degrees; shelf life 180 days
Host rat
Clone NZ-1.2
Application(s)

FC and WB

Formulation 100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
Custom Code 3822.00
UNSPSC code 12352203

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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