TIM4 Monoclonal Antibody

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Cat No: 10322

T cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

t-cell t cell mucin trans membrane protein immune responses allergy asthma transplant tolerance viral infections dendritic macrophages phosphatidylserine T helper type 2 Th2 immunity TIM-4 TIM 4 TIMs TIMD-4 TIM D4 TIMD4

Product Overview:
T cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity, and viral infections.{21964} TIM4 is expressed on dendritic cells and macrophages, and these proteins bind tightly to phosphatidylserine on apoptotic cells and enhance their engulfment by macrophages.{15136} It also plays an important role in the proliferation of T helper type 2 cells.{21966} TIM4 is the natural ligand of TIM1, and this binding regulates T cell proliferation.{21967} TIM4 expressing cells also regulate adaptive immunity.{21965}

Size	1 ea
Shipping	dry ice
Host	Armenian hamster
Antigen	TIM4 from mouse peritoneal cells
Application(s)	FC and ICC
Formulation	400 µg of protein A-purified monoclonal antibody
Custom Code	3822.19
UNSPSC code	12352203

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.