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IP6K2 Monoclonal Antibody (Clone 4F10)

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    IP6K2 Monoclonal Antibody (Clone 4F10)
  • IP6K2 Monoclonal Antibody (Clone 4F10)
Cat No: 10239
Antibodies - Monoclonal Antibodies
Cayman
€342.00
Price is excluding VAT and does not include packaging neither shipping

Inositol hexakisphosphate kinase 2 (IP6K2) is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP.{22131} IP6K2 functions as a proapoptotic protein kinase.{22130} IP6K2 binds to tumor...

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: 1 ea

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Correlated keywords:
  • cytoplasmic kinases inositol phosphates IP6 InsP5PP proapoptotic tumor necrosis factor HSP90 TNF TRAF cancer HSPs 90
Product Overview:
Inositol hexakisphosphate kinase 2 (IP6K2) is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP.{22131} IP6K2 functions as a proapoptotic protein kinase.{22130} IP6K2 binds to tumor necrosis factor receptor-associated factor 2 and inhibits NF-κB signaling.{22139} Heat Shock Protein 90 regulates apoptosis through a normal physiological interaction with IP6K2 by inhibiting its catalytic activity.{22128} Thus, IP6K2 is a potential target for cancer therapeutics development.{22128}
Size 1 ea
Shipping dry ice
Stability Store at -20 degrees; shelf life 365 days
Host Mouse
Antigen Human IP6K2 protein
Clone 4F10
Isotype IgG2b
Application(s)

ICC and WB

Formulation 200 µg lyophilized protein A-purified monoclonal antibody
Custom Code 3822.00
UNSPSC code 12352203

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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