CD3 Monoclonal FITC Antibody (Clone RIV9)

Cat No: 10231

The CD3 antigen is a specific T-cell marker expressed on thymocytes and mature T-lymphocytes. The CD3 complex contains CD3g (Mr = 26 kDa), CD3d (Mr = 21 kDa), and CD3e (Mr = 20 kDa).{16550} CD3 is detected on the surface membrane or in the cytoplasm o...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

antibodies antigens flow cytometry FC immunocytochemistry ICC immunohistochemistry IHC frozen sections T-cells IF immunofluorescence

Product Overview:
The CD3 antigen is a specific T-cell marker expressed on thymocytes and mature T-lymphocytes. The CD3 complex contains CD3g (Mr = 26 kDa), CD3d (Mr = 21 kDa), and CD3e (Mr = 20 kDa).{16550} CD3 is detected on the surface membrane or in the cytoplasm of T-cells from peripheral blood, depending on the state of cell differentiation. In addition to detection of T-cells from peripheral blood, the CD3 antibody can be used for detection of reactive T-cells in lymphoid infiltrates in tissues and neoplastic T-cells in non-Hodgkin’s lymphomas of T-cell lineage.{12060,16551}

Size	1 ea
Shipping	dry ice
Host	Mouse
Clone	RIV9
Application(s)	(+) FC, IF, and IHC (frozen sections); (?) IHC (paraffin-embedded tissue) and WB
Formulation	100 µg of fluorescein-labeled IgG3 in 500 µl PBS, pH 7.2, containing 50% glycerol, 0.1% BSA, and 0.02% sodium azide
Custom Code	3822.19
UNSPSC code	12352203

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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