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GPR55 Blocking Peptide

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Cat No: 10225
Antibodies - Blocking Peptides
Cayman
€141.00
Price is excluding VAT and does not include packaging neither shipping

GPR55 is a G protein-coupled receptor that has been identified as a novel cannabinoid receptor, although its exact role is still controversial.{17583,14747} Previously central cannabinoid (CB1) and peripheral cannabinoid (CB2), two widely characterize...

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: 200 µg

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Product Overview:
GPR55 is a G protein-coupled receptor that has been identified as a novel cannabinoid receptor, although its exact role is still controversial.{17583,14747} Previously central cannabinoid (CB1) and peripheral cannabinoid (CB2), two widely characterized receptors have been shown to bind THC the active component of cannabis and other endocannabinoids. Mounting evidence suggests that additional receptors play a role in CB-related signal transduction and GPR55 has been identified as one of them.{17581} This receptor is widely expressed in the brain, specifically found in large dorsal root ganglion neurons.{17584} Along with binding THC, it also shows high affinity to anandamide, methanandamide, JWH 015, and many other CB ligands.{15021,17582} The human protein shows 75% and 78% overall sequence homology with the rat and murine proteins, respectively.{17583} GPR55 is composed of 319 amino acids and has an expected molecular weight of 37 kDa. Post-translational modifications such as glycosylation may retard receptor electrophoretic migration and thereby protein signal may be detected above 37 kDa.
Size 200 µg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
Formulation 200 µg of peptide in 200 μl TBS, pH 7.4, containing 0.1% BSA, and 0.02% sodium azide
Custom Code 3504.00
UNSPSC code 12352203

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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