COX Inhibitor Pack

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COX Inhibitor Pack

Cat No: 10186

Biochemicals - Small Molecule Inhibitors

The Cayman COX Inhibitor Pack contains a combination of frequently used cyclooxygenase (COX) inhibitors. Each kit contains aspirin, the archetype nonselective, irreversible COX inhibitor.{816} A series of COX-2 selective inhibitors are available in th...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

cyclooxygenases PGHS-2 inducible synthases prostaglandins CAY10404 SC-560 SC-58125 valeroyl saliylate NS-398 aspirin resveratrol APHS inhibitors inhibits inhibition SC560 SC58125 NS 398 COX-2 COX2 COX-1 COX1 PGHS2 PGHS-1 PGHS1 10186 70330 70655 10006120 10007692 valdecoxib licofelone packs

Product Overview:
The Cayman COX Inhibitor Pack contains a combination of frequently used cyclooxygenase (COX) inhibitors. Each kit contains aspirin, the archetype nonselective, irreversible COX inhibitor.{816} A series of COX-2 selective inhibitors are available in the COX-PAK, including NS-398, one of the first reported and most widely used.{1222} Another COX-2-selective inhibitor included is CAY10404, with nearly 500,000-fold COX-2 selectivity.{8944} The potent COX-1-selective inhibitor SC-560 is an example of a reversible, diaryl heterocycle COX-1 inhibitor with low nM activity.{7675} Also included is valeroyl salicylate, an irreversible alkylator of COX enzymes with some selectivity toward COX-1.{1284} Resveratrol is also included in the COX-PAK due to its complex activities, which include COX inhibition, peroxidase inhibition, antioxidant activity, and gene regulation.{6817,3491}

Size	1 ea
Shipping	dry ice
Purity	≥98%
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.