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OMDM-1

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    OMDM-<wbr/>1
  • OMDM-<wbr/>1
Cat No: 10171
Biochemicals - More Biochemicals
Cayman
€13.00
Price is excluding VAT and does not include packaging neither shipping

Numerous analogs of arachidonoyl ethanolamide{10254} (AEA, anandamide; Item No. 90050) potentiate its biological activity. This potentiation is ascribed either to inhibition of AEA reuptake into neurons or inhibition of fatty acid amide hydrolase (FAAH...

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Territorial Availability: Available through Bertin Pharma only in Europe
Synonyms:
  • (S)-N-(1-(4-hydroxyphenyl)-2-hydroxyethyl)oleamide
Correlated keywords:
  • endocannabinoids inhibitors AEA lipids anandamides analogs selective selectivity inhibits inhibition R-tyrosinol amides (R)-tyrosinol oleic acid reuptake OMDM1 neurochemistry neuroscience cannabinoids inhibitors
Product Overview:
Numerous analogs of arachidonoyl ethanolamide{10254} (AEA, anandamide; Item No. 90050) potentiate its biological activity. This potentiation is ascribed either to inhibition of AEA reuptake into neurons or inhibition of fatty acid amide hydrolase (FAAH) within the neurons.{10647} OMDM-1 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of the cellular uptake of AEA.{11240} Structurally, OMDM-1 is the amide of (S)-tyrosinol with oleic acid (Item No. 90260). In RBL-2H3 cells, OMDM-1 inhibits the cellular uptake of tritiated AEA with an IC50 of 2.4 µM, with negligible effects on the CB1 receptor and VR1.{11240}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 616884-62-9
Molecular Formula C27H45NO3
SMILES CCCCCCCC/C=C\CCCCCCCC(=O)N[C@H](CO)Cc1ccc(O)cc1
Molecular Weight 431,7
Formulation A crystalline solid
Purity ≥98%
Custom Code 2924.19
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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