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15-deoxy-?12,14-Prostaglandin J2-biotin

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    15-<wbr/>deoxy-<wbr/>?<sup>12,14</sup>-<wbr/>Prostaglandin J<sub>2</sub>-<wbr/>biotin
  • 15-<wbr/>deoxy-<wbr/>?<sup>12,14</sup>-<wbr/>Prostaglandin J<sub>2</sub>-<wbr/>biotin
Cat No: 10141

15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2; Item No. 18570) is one of the cyclopentenone PGs, which have documented metabolic (peroxisome proliferator-activated receptor γ-activating), antimitotic, and antiproliferative effects.{410,1349,1...


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Territorial Availability: Available through Bertin Technologies only in France
  • N-11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oyl-N’-biotinoyl-1,5-diaminopentane
Correlated keywords:
  • affinity probes binding proteins cyclopentenones PGs prostaglandins peroxisomes proliferator-activated receptors PPARs anitmitotic antiproliferative genes expressions non-classical non-GPCR gene protein-coupled detected detection interactions biotins ligands complexes nuclear nucleic acids elucidations mechanisms biotinylated PGJ2 biotinamides
Product Overview:
15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2; Item No. 18570) is one of the cyclopentenone PGs, which have documented metabolic (peroxisome proliferator-activated receptor γ-activating), antimitotic, and antiproliferative effects.{410,1349,13037} The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical (i.e., non-G protein-coupled receptor) pathways. 15-deoxy-Δ12,14-PGJ2-biotin is an affinity probe which allows 15-deoxy-Δ12,14-PGJ2 to be detected through an interaction with the biotin ligand. 15-deoxy-Δ12,14-PGJ2-biotin was designed to allow 15-deoxy-Δ12,14-PGJ2 to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs.
Size 50 µg
Shipping dry ice
Molecular Formula C35H54N4O4S
Molecular Weight 626,9
Formulation A solution in ethanol
Purity ≥98%
Custom Code 2937.50
UNSPSC code 12352100

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