Thromboxane B2-biotin

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Thromboxane B₂-biotin

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Cat No: 9002298

Thromboxane A2 (TXA2) is produced from arachidonic acid (Item No. 90010) by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle.{487,6062,6063} TXA2 is rapidly hydrolyzed non-enzymatically to ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(Z)-7-((2R,3S,4S)-4,6-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)tetrahydro-2H-pyran-3-yl)-N-(5-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)pentyl)hept-5-enamide

Correlated keywords:

biochemical eicosanoid fatty acid lipid mediator thromboxane reactive probe affinity TXB2 binding partner TXB-2

Product Overview:
Thromboxane A2 (TXA2) is produced from arachidonic acid (Item No. 90010) by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle.{487,6062,6063} TXA2 is rapidly hydrolyzed non-enzymatically to TXB2 (Item No. 19030), which is then quickly metabolized to urinary metabolites for clearance by the kidneys. TXB2-biotin is an affinity probe which allows TXB2 to be detected through an interaction with the biotin ligand. It was designed to allow TXB2 to be detected in complexes with protein binding partners.

Size	50 µg
Shipping	dry ice
Molecular Formula	C₃₅H₆₀N₄O₇S
SMILES	O[C@@H]1[C@H](C/C=C\CCCC(NCCCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C1
Molecular Weight	681
Formulation	A solution in ethanol
Purity	≥90%
Custom Code	2937.50
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.