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SB-242084 (hydrochloride)

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    SB-242084 (hydro<wbr>chloride)
  • SB-242084 (hydro<wbr>chloride)
Cat No: 10096
Biochemicals - Receptor Pharmacology

Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that activates specific receptors located primarily in the gut and central nervous system. SB-242084 is an antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivit...


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Territorial Availability: Available through Bertin Technologies only in France
  • 6-chloro-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide, dihydrochloride
Correlated keywords:
  • 181632-25-7 serotonins 5-hydroxytryptamines 5-HT neurotransmitters neuroscience receptors gut central nervous system antagonists 5-HT2C dopamine adrenergic receptors brain anxiolytic neurochemistry CNS Antigens HLA-SB Antigens HLA-PL Antigens HLA-DP HLA-SB Antigens HLA-PL Antigens HLA-DP Antigens HLA SB Antigens HLA PL Antigens HLA DP Antigens HLA-SB HLA-PL HLA-DP
Product Overview:
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that activates specific receptors located primarily in the gut and central nervous system. SB-242084 is an antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors.{18221,18225} In vivo, it is brain penetrant and has significant anxiolytic activity, without sedative, proconvulsant, or hyperphagic properties.{18221} SB-242084 has been used extensively in animal research to evaluate, for example, 5-HT2C receptor agonists and neurotransmitter receptor interactions in mice.{18222,18223,18224}
Size 1 mg
Shipping dry ice
CAS Number 1049747-87-6
Molecular Formula C21H19ClN4O2 • 2HCl
Molecular Weight 467,8
Formulation A crystalline solid
Purity ≥98%
Custom Code 2933.39
UNSPSC code 12352100

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