Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

N-(α-Linolenoyl) Tyrosine

  • Zoom
    N-<wbr/>(α-<wbr/>Linolenoyl) Tyrosine
  • N-<wbr/>(α-<wbr/>Linolenoyl) Tyrosine
Cat No: 10032
Biochemicals - Lipids
Cayman
€75.00
Price is excluding VAT and does not include packaging neither shipping

Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simpl...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Pharma only in Europe
Synonyms:
  • N-(L-tyrosine)-9Z,12Z,15Z-octadecatrienamide
Correlated keywords:
  • neurochemistry neuroscience fatty acids neurotransmitters dopamine CNS central nervous system anti-Parkinson's anti-Parkinsons diseases endocrinology
Product Overview:
Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.{10323} In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.{10323}
Size 5 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 365 days
CAS Number 259143-19-6
Molecular Formula C27H39NO4
SMILES CC/C=C\C/C=C\C/C=C\CCCCCCCC(N([C@H](C(O)=O)CC1=CC=C(O)C=C1)[H])=O
Molecular Weight 441,6
Formulation A solution in ethanol
Purity ≥98%
Custom Code 2916.15
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : N-<wbr/>(α-<wbr/>Linolenoyl) Tyrosine There are 6 products.

Search