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Cyclopentenone Prostaglandin HPLC Mixture

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Cat No: 10000
Biochemicals - Lipids
Cayman

This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: 100 µg of each compound Prostaglandin A2 (Item No. 10210) Prostaglandin B2 (Item No. 11210) Prostaglandin D2 (Item No. 12010) Prostagl...

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: 1 ea

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Territorial Availability: Available through Bertin Technologies only in France
Correlated keywords:
  • PGA2 PGB2 PGD2 PGE2 15-deoxy-.DELTA.12,14-PGJ2 prostaglandins mixtures chromatography 15-deoxy-delta12,14-PGJ2 cyclopentenones UV-absorbing 15-deoxy-d12,14-PGJ2
Product Overview:
This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: 100 µg of each compound Prostaglandin A2 (Item No. 10210) Prostaglandin B2 (Item No. 11210) Prostaglandin D2 (Item No. 12010) Prostaglandin E2 (Item No. 14010) Prostaglandin J2 (Item No. 18500) 15-deoxy-Δ12,14-Prostaglandin J2 (Item No. 18570) PGE2 and PGD2 are both chemically unstable. In the absence of any enzymatic influence, both are undergo dehydration to form the highly UV active cyclopentenone compounds PGA2 and PGJ2, respectively.{1593,1742} These compounds absorb in the ultraviolet with maxima at 216 - 220 lambda. The cyclopentenone prostaglandins have been noted to have antimitotic, antiviral and antitumor activity in a number of systems.{335,870} PGA2 and PGJ2, can also undergo further elimination and double bond rearrangements to give PGB2 and 15-deoxy-Δ12,14 PGJ2, respectively. 15-deoxy-Δ12,14 PGJ2 is a relatively potent ligand for the PPARγ nuclear receptor. PGB2 does not appear to have significant intrinsic biological activity; however, it is frequently used as a reliable internal standard for analysis of eicosanoids by HPLC.
Size 1 ea
Shipping dry ice
Formulation A solution in methyl acetate
Purity ≥98% for each compound
Custom Code 3822.19
UNSPSC code 12352100

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