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Cyclopentenone Prostaglandin HPLC Mixture

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Cat No: 10000
Biochemicals - Lipids
Cayman
€88.00
Price is excluding VAT and does not include packaging neither shipping

This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: 100 µg of each compound Prostaglandin A2 (Item No. 10210) Prostaglandin B2 (Item No. 11210) Prostaglandin D2 (Item No. 12010) Prostagla...

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: 1 ea

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Correlated keywords:
  • PGA2 PGB2 PGD2 PGE2 15-deoxy-.DELTA.12,14-PGJ2 prostaglandins mixtures chromatography 15-deoxy-delta12,14-PGJ2 cyclopentenones UV-absorbing 15-deoxy-d12,14-PGJ2
Product Overview:
This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: 100 µg of each compound Prostaglandin A2 (Item No. 10210) Prostaglandin B2 (Item No. 11210) Prostaglandin D2 (Item No. 12010) Prostaglandin E2 (Item No. 14010) Prostaglandin J2 (Item No. 18500) 15-deoxy-Δ12,14-Prostaglandin J2 (Item No. 18570) PGE2 and PGD2 are both chemically unstable. In the absence of any enzymatic influence, both are undergo dehydration to form the highly UV active cyclopentenone compounds PGA2 and PGJ2, respectively.{1593,1742} These compounds absorb in the ultraviolet with maxima at 216 - 220 lambda. The cyclopentenone prostaglandins have been noted to have antimitotic, antiviral and antitumor activity in a number of systems.{335,870} PGA2 and PGJ2, can also undergo further elimination and double bond rearrangements to give PGB2 and 15-deoxy-Δ12,14 PGJ2, respectively. 15-deoxy-Δ12,14 PGJ2 is a relatively potent ligand for the PPARγ nuclear receptor. PGB2 does not appear to have significant intrinsic biological activity; however, it is frequently used as a reliable internal standard for analysis of eicosanoids by HPLC.
Size 1 ea
Shipping dry ice
Stability Store at -80 degrees; shelf life 180 days
Formulation A solution in methyl acetate
Purity ≥98% for each compound
Custom Code 3822.00
UNSPSC code 12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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