L-Glutathione, oxidized (sodium

Confirm delete?

L-Glutathione, oxidized (sodium salt)

Zoom

Cat No: 15491

Biochemicals - Ox Stress Reagents

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell.{11632} GSSG is the oxidized form of GSH (Item No. 10007...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

L-?-glutamyl-L-cysteinyl-bimol-(2?2')-disulfide-glycine, disodium salt

Correlated keywords:

27025-41-8 1033693-?26-?3 glutathiol GSSG glutathione disulfide oxidative injury stress redox antioxidant S-glutathionylation hydrogen acceptors GSH oxidized NADPH NADPH sodium salts gluthoxim glutoxim NOVs 002 glycine NOV002 NOV-002

Product Overview:
Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell.{11632} GSSG is the oxidized form of GSH (Item No. 10007461). It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase.{11632} GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications.{25273} The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress.{25274}

Size	100 mg
Shipping	dry ice
CAS Number	103239-24-3
Molecular Formula	C₂₀H₃₀N₆O₁₂S₂ • 2Na
SMILES	O=C([C@@H](NC(CC[C@@H](C([O-])=O)N)=O)CSSC[C@H](NC(CC[C@@H](C([O-])=O)N)=O)C(NCC(O)=O)=O)NCC(O)=O.[Na+].[Na+]
Molecular Weight	656,6
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.