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Thromboxane B2 MaxSpec® Standard

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    Thromboxane B<sub>2</sub> MaxSpec<sup>®</sup> Standard
  • Thromboxane B<sub>2</sub> MaxSpec<sup>®</sup> Standard
Cat No: 10007237
Biochemicals - Analytical Standards
Cayman
€125.00
Price is excluding VAT and does not include packaging neither shipping

Thromboxane B2 (TXB2) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds.{488} Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis,{6304} while meas...

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: 100 µg

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid
Correlated keywords:
  • platelet metabolite TXB2 intrarenal TXA2 urine urinary atherosclerosis MS quantitative standard mass spec spectrometry lipidomics LC-MS
Product Overview:
Thromboxane B2 (TXB2) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds.{488} Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis,{6304} while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of systemic TXA2 secretion.{717,868} TXB2 MaxSpec® standard is a quantitative grade standard of TXB2 (Item No. 19030) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This TXB2 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Size 100 µg
Shipping dry ice
Stability Store at -20 degrees; shelf life 1095 days
CAS Number 54397-85-2
Molecular Formula C20H34O6
SMILES CCCCCC(O)/C=C/[C@H]1OC(O)CC(O)C1C/C=C\CCCC(=O)O
Molecular Weight 370,5
Formulation A solution in methyl acetate at 100 µg/ml
Purity ≥95%
Custom Code 3822.00
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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