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C16 Sphingomyelin (d18:1/16:0)

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    C16 Sphingomyelin (d18:1/16:0)
  • C16 Sphingomyelin (d18:1/16:0)
Cat No: 10007946
Biochemicals - Lipids
Cayman
€74.00
Price is excluding VAT and does not include packaging neither shipping

Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. C16 Sphingomyelin is a naturally occurring sphingolipid.{37418,40751,37417} Levels of C16 sphingomyelin are elevated in ...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 4-hydroxy-7S-[1R-hydroxy-2E-hexadecenyl]-N,N,N-trimethyl-9-oxo-4-oxide-3,5-dioxa-8-aza-4-phosphatetracosan-1-aminium
Correlated keywords:
  • membranes lipids sphingosines eggs brains cholesterol rafts ceramides sphingolipids apoptosis 16:0 SM (d18:1/16:0) hexadecanoyl sphingomyelin N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine PCs
Product Overview:
Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. C16 Sphingomyelin is a naturally occurring sphingolipid.{37418,40751,37417} Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease.{37418,40751} Plasma levels of C16 sphingomyelin are decreased in patients with prostate cancer.{37417} Model membranes containing C16 sphingomyelin, 1-palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC; Item No. 15102), and cholesterol (Item No. 9003100) have been used in the study of lipid raft dynamics and membrane organization.{48564,48565}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 6254-89-3
Molecular Formula C39H79N2O6P
SMILES CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O
Molecular Weight 703
Formulation A crystalline solid
Purity ≥98%
Custom Code 2915.90
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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