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Mefenamic Acid

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    Mefenamic Acid
  • Mefenamic Acid
Cat No: 23650
Biochemicals - Small Molecule Inhibitors
Cayman

Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and a COX-2 inhibitor.{41197} It binds to COX-2 (Kd = 4 nM) and inhibits COX-2-dependent oxygenation of arachidonic acid (Item Nos. 90010
90010.1
10006607) in vitro (Ki = 10 µM). Mef...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 2-[(2,3-dimethylphenyl)amino]-benzoic acid
Correlated keywords:
  • Bafameritin Baphameritin Bonabol CI473 CI 473 CN35355 Coslan InM INF 3355 INF3355 Lysalgo Mefacit Mefenacid Mephenamic Namphen NSC94437 Parkemed Ponalar Ponstan Ponstel Ponstil Ponstyl Pontal Relafan Tanston Vialidon anthranilic COX2
Product Overview:
Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and a COX-2 inhibitor.{41197} It binds to COX-2 (Kd = 4 nM) and inhibits COX-2-dependent oxygenation of arachidonic acid (Item Nos. 90010
90010.1
10006607) in vitro (Ki = 10 µM). Mefenamic acid (30 mg/kg) reduces acetic acid-induced writhing in rats.{41198} It inhibits increases in skin thickness in a mouse model of delayed-type hypersensitivity induced by dinitrochlorobenzene (DNBC).{41198} Mefenamic acid also reduces the antibody response to sheep red blood cells in mice.
Size 25 mg
Shipping wet ice
CAS Number 61-68-7
Molecular Formula C15H15NO2
SMILES CC1=CC=CC(NC2=CC=CC=C2C(O)=O)=C1C
Molecular Weight 241,3
Formulation A solid
Purity ≥98%
Custom Code 2922.49
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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