Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

Nicotinamide riboside

  • Zoom
    Nicotinamide riboside
  • Nicotinamide riboside
Cat No: 23132
Biochemicals - Small Molecule Activators
Cayman
€33.00
Price is excluding VAT and does not include packaging neither shipping

Nicotinamide riboside is a riboside form of nicotinamide (Item No. 11127) that is found in trace amounts in yeast-containing and milk-derived products.{38460} It is a precursor of NAD+ (Item No. 16077) and a source of vitamin B3 (niacin). Nicotinamide...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 3-(aminocarbonyl)-1-β-D-ribofuranosyl-pyridinium
Correlated keywords:
  • 19131-72-7 20299-13-2 954368-04-8 ribose ribonucleoside Ribosyl HEK-293 Hepa-1.6 FOX-O1 SOD-2 SIRT-1 2 3 Ribosylnicotinamide adenine dinucleotide C2C-12 forkhead box class O1 Superoxide dismutase
Product Overview:
Nicotinamide riboside is a riboside form of nicotinamide (Item No. 11127) that is found in trace amounts in yeast-containing and milk-derived products.{38460} It is a precursor of NAD+ (Item No. 16077) and a source of vitamin B3 (niacin). Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1,000 μM.{38461} It also decreases acetylation of FOXO1 and SOD2, which are substrates of sirtuin 1 (SIRT1) and SIRT3, respectively, but not the SIRT2 substrate tubulin, indicating nicotinamide riboside selectively enhances SIRT1 and 3 deacetylase activity. Nicotinamide riboside (400 mg/kg per day) increases NAD+ levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet. It also increases NAD+ in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.{38462}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 1341-23-7
Molecular Formula C11H15N2O5
SMILES NC(C1=C[N+]([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)=CC=C1)=O
Molecular Weight 255,3
Formulation A low melting semi-solid
Purity ≥95%
Custom Code 2933.39
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Nicotinamide riboside There are 2 products.

Search