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Diclofenac (diethylamine)

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    Diclofenac (diethylamine)
  • Diclofenac (diethylamine)
Cat No: 22983
Biochemicals - Small Molecule Inhibitors
Cayman
€33.00
Price is excluding VAT and does not include packaging neither shipping

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 µM, respectively.{39325,1791,1286} Formulations containing diclofenac reduce inflammation and pain associated with ost...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid compd. with N-monoethylethanamine
Correlated keywords:
  • 15307-86-5 antiinflammatory nonsteroidal COX1 COX2 Atomo Desinflamante Ethanamine Emulgel Voltaren Schmerzgel diethylammonium ammonium diethyl
Product Overview:
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 µM, respectively.{39325,1791,1286} Formulations containing diclofenac reduce inflammation and pain associated with osteoarthritis, rheumatoid arthritis, gout, and ankylosing spondylitis.{1791,1286,39326} Diclofenac (diethylamine) has increased ex vivo skin permeability over diclofenac (sodium salt) (Item No. 70680), and topical formulations containing diclofenac (diethylamine) have been used to decrease pain without the gastrointestinal side effects associated with oral administration in patients with rheumatoid arthritis.{39326,39325}
Size 1 g
Shipping wet ice
Stability Store at 4 degrees; shelf life 730 days
CAS Number 78213-16-8
Molecular Formula C14H11Cl2NO2 • C4H11N
SMILES ClC1=C(NC2=C(CC(O)=O)C=CC=C2)C(Cl)=CC=C1.CCNCC
Molecular Weight 369,3
Formulation A crystalline solid
Purity ≥98%
Custom Code 2903.99
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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