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Dexamethasone-d4

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    Dexamethasone-d<sub>4</sub>
  • Dexamethasone-d<sub>4</sub>
Cat No: 22100
Biochemicals - Isotopically Labeled Standards
Cayman
€73.00
Price is excluding VAT and does not include packaging neither shipping

Dexamethasone-d4 is intended for use as an internal standard for the quantification of dexamethasone (Item No. 11015) by GC- or LC-MS. Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 9-fluoro-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione-4,6,21,21-d4
Correlated keywords:
  • 50-02-2 8054-59-9 137098-19-2 906362-70-7 906422-84-2 1050677-47-8 adexone aeroseb-dex aphtasolon aphthasolone azium calonat corsone cortisumman decacort decaderm decadron-a decalix decasone dekacort dekort delipos deltafluorene dergramin deronil desadrene desameton deseronil dexa-cortidelt mamallet scheroson sine dexacort dexacortal dexacortin dexadeltone dexafarma dexalona dexaltin dexameth dexamonozon dexapolcort dexapos dexaprol dexaratiopharm dexason dexasone dexaven dexinoral dexium dexmethsone dexone dexonium dextelan dinormon diodex etacortilen fluormethylprednisolone fluormone fluorocort gammacorten gentalipos HL hexadecadrol hexadrol isopto lokalison-F loverine luxazone MK-125 MK125 maxidex millicorten minidex NSC34521 NSC-34521 oradexon ozurdex pet-derm III 3 posurdex prednisolon prednisolone superprednol surodex visumetazone deuterated LCMS LC/MS GC-MS GCMS GC/MS antiinflammatory
Product Overview:
Dexamethasone-d4 is intended for use as an internal standard for the quantification of dexamethasone (Item No. 11015) by GC- or LC-MS. Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively).{20150} Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in general, anti-inflammatory results.{20149}
Size 500 µg
Shipping dry ice
Molecular Formula C22H25D4FO5
SMILES O=C1C=C[C@@]2(C)C(C([2H])C[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(C([2H])([2H])O)=O)=C1[2H]
Molecular Weight 396,5
Formulation A solid
Purity ≥99% deuterated forms (d1-d4)
Custom Code 3822.00
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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