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Cangrelor (sodium salt)

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    Cangrelor (sodium salt)
  • Cangrelor (sodium salt)
Cat No: 22086
Biochemicals - Receptor Pharmacology
Cayman

Cangrelor is an ATP analog that inhibits platelet aggregation (IC50 = 0.4 nM).{40206} It is a reversible competitive antagonist of the platelet purinergic P2Y12 receptor.{23699,40207} Pretreatment with cangrelor significantly reduces blood clotting in...

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: 1 mg

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-5'-adenylic acid, anhydride with P,P'-(dichloromethylene)bis[phosphonic acid], tetrasodium salt
Correlated keywords:
  • 163706-06-7 ARC 69931MX ARC69931 MX ARC69931MX KENGREAL
Product Overview:
Cangrelor is an ATP analog that inhibits platelet aggregation (IC50 = 0.4 nM).{40206} It is a reversible competitive antagonist of the platelet purinergic P2Y12 receptor.{23699,40207} Pretreatment with cangrelor significantly reduces blood clotting induced by ADP in a mouse model of pulmonary thromboembolism.{40208} Formulations containing cangrelor have been used to prevent blood clotting in at-risk patients.{40209}
Size 1 mg
Shipping dry ice
CAS Number 163706-36-3
Molecular Formula C17H21Cl2F3N5O12P3S2 • 4Na
SMILES O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(SCCC(F)(F)F)N=C3NCCSC)O[C@@H]1COP(OP(C(Cl)(Cl)P([O-])([O-])=O)([O-])=O)([O-])=O.[Na+].[Na+].[Na+].[Na+]
Molecular Weight 864,3
Formulation A solid
Purity ≥98%
Custom Code 2932.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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