Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

TTNPB

  • Zoom
    TTNPB
  • TTNPB
Cat No: 16144
Biochemicals - Receptor Pharmacology
Cayman
€46.00
Price is excluding VAT and does not include packaging neither shipping

TTNPB is an analog of retinoic acid (Item No. 11017) that potently and selectively activates retinoic acid receptors (EC50s = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively).{27011,23075} It does not act on retinoid X receptors and weakly ag...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]-benzoic acid
Correlated keywords:
  • 111035-​66-​6 101204-37-9 110917-84-5 receptors agonists signals transductions stems cells research nuclear retinoic acids RARs actions epidermal proliferation embryogenesis differentiation potent selective AGNs 191183 AGN191183 AGN-191183 arotinoid Ros 13-7410 137410 Ro-13-7410 Ro-137410 Ro13-7410 Ro137410 Ro-13 7410 Ro13 13 biochemicals RARα RARβ RARγ RAR-α RAR-β RAR-γ α β γ
Product Overview:
TTNPB is an analog of retinoic acid (Item No. 11017) that potently and selectively activates retinoic acid receptors (EC50s = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively).{27011,23075} It does not act on retinoid X receptors and weakly agonizes farnesoid X receptor (EC50 > 1 µM).{23075,12563} TTNPB is used to study RAR action in diverse processes, including epidermal cell proliferation, embryogenesis, and stem cell differentiation.{27013,27012,25645,27014}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 71441-28-6
Molecular Formula C24H28O2
SMILES CC1(C)C2=C(C=CC(/C(C)=C/C3=CC=C(C(O)=O)C=C3)=C2)C(C)(C)CC1
Molecular Weight 348,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2916.39
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : TTNPB There are 10 products.

Search