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Calcipotriol (hydrate)

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    Calcipotriol (hydrate)
  • Calcipotriol (hydrate)
Cat No: 10009599
Biochemicals - Receptor Pharmacology

Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3).{15198} Binding of calcipotriol (hydrate) to the VDR incr...


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Territorial Availability: Available through Bertin Technologies only in France
  • 24-cyclopropyl-(1?,3?,5Z,7E,22E,24S)-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol, monohydrate
Correlated keywords:
  • vitamins D3 receptors calcium calcitriols JunB inflammations psoriasis skin irritations keratinocyte cells proliferations differentiations T immune response 112828-00-9 112965-21-6
Product Overview:
Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3).{15198} Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response.{15197} Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.{15196}
Size 10 mg
Shipping dry ice
CAS Number 147657-22-5
Molecular Formula C27H40O3 • H2O
SMILES C=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2CCC[C@@]3(C)[C@@]\2([H])CC[C@]3([H])[C@H](C)/C=C/[C@@H](O)C4CC4.O
Molecular Weight 430,6
Formulation A crystalline solid
Purity ≥98%
Custom Code 2907.29
UNSPSC code 12352100

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