H2AX Phospho-Ser 139 (1H2) Monoclonal Antibody

Antibodies - Monoclonal Antibodies

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Cat No: G01106

Antibodies - Monoclonal Antibodies

DNA double strand break (DSB) are leading to the early phosphorylation of Histone H2AX. Phosphorylated Gamma-H2AX is the first step in the recruitment of the DNA repair protein at the foci site. They are consequently very good biomarkers of DNA double ...

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                        Territorial Availability: Available worldwide directly through Bertin or your local distributor
                    

Synonyms:

γH2AX

gamma H2AX

Correlated keywords:

Transcription Factor Related

phosphorylation

nucleosome

core

histone

H-2A

H2-A

H-2-A

H2AX

H2-AX

H-2-AX

serine

Ser139

Ser-139

phospho-γH2AXSer139

γH2AXSer139

γH2AXSer-139

γH2AX-Ser-139

γH2AX

γH2-AX

γH-2-AX

Product Overview:
DNA double strand break (DSB) are leading to the early phosphorylation of Histone H2AX. Phosphorylated Gamma-H2AX is the first step in the recruitment of the DNA repair protein at the foci site. They are consequently very good biomarkers of DNA double strand break as well as check point for cell cycle arrest following DSB.
Measuring gamma-H2AX phosphorylation has become a gold standard in DNA damage and repair for DSB events.

Size	100 µL
Shipping	wet ice
Host	mouse
Antigen	Recombinant TLF protein
Clone	14HH2-1H2
Isotype	IgG1, ҡ
Application(s)	ELISA Western Blot Immunocytochemistry Recommended dilutions: 1/500-1/5000
Specificity	mouse and human Histone H2 phosphorilated on Ser 139
Application Media	ELISA\|WesternBlot\|Immunohistochemistry\|recommended dilution from 1/500 to 1/5000
Formulation	Liquid Ascite, does not contain any preservative therefore avoid repeat freezing and thawing cycles
Custom Code	3822000000
UNSPSC code	12352203