Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

1-NBD-decanoyl-2-decanoyl-sn-Glycerol

  • Zoom
    1-<wbr/>NBD-<wbr/>decanoyl-<wbr/>2-<wbr/>decanoyl-<wbr/><em>sn</em>-<wbr/>Glycerol
  • 1-<wbr/>NBD-<wbr/>decanoyl-<wbr/>2-<wbr/>decanoyl-<wbr/><em>sn</em>-<wbr/>Glycerol
Cat No: 9000341
Biochemicals - Labeling & Detection
Cayman
€129.00
Price is excluding VAT and does not include packaging neither shipping

Diacylglycerols (DAG) are produced by the hydrolysis of membrane phospholipids. They act as lipid second messengers, activating PKC and regulating cell growth and apoptosis. They also serve as substrates for DAG kinases for the production of phosphati...

More

This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 1-NBD-1,2-bis(O-decanoyl-sn-glycerol)
Correlated keywords:
  • fluorescent DAG PKC second messengers diacylglycerols signaling activator ERK MAPK RasGRP binding
Product Overview:
Diacylglycerols (DAG) are produced by the hydrolysis of membrane phospholipids. They act as lipid second messengers, activating PKC and regulating cell growth and apoptosis. They also serve as substrates for DAG kinases for the production of phosphatidic acid, another important lipid messenger. 1-NBD-decanoyl-2-decanoyl-sn-glycerol has the fluorophore nitrobenzoxadiazole (NBD) attached to the ω-end of the terminal decanoyl chain of the model diacylglycerol (DAG), 1,2-didecanoyl-sn-glycerol. 1-NBD-decanoyl-2-decanoyl-sn-glycerol is likely to have excitation/emission maxima of approximately 470/541 nm, respectively, based on the maxima of various NBD-labeled phospholipids.{39414} Fluorescently-tagged lipids have been used to study their interactions with proteins, their utilization by cells and liposomes, and for the development of assays for lipid metabolism.{16838,12304,16839,13590,14063}
Size 500 µg
Shipping dry ice
Stability Store at -80 degrees; shelf life 365 days
Molecular Formula C29H46N4O8
SMILES CCCCCCCCCC(=O)O[C@@H](CO)COC(=O)CCCCCCCCCNc1ccc([N](=O)O)c2nonc12
Molecular Weight 578,7
Formulation A solution in ethanol
Purity ≥98%
Custom Code 2905.59
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : 1-<wbr/>NBD-<wbr/>decanoyl-<wbr/>2-<wbr/>decanoyl-<wbr/><em>sn</em>-<wbr/>Glycerol There are 4 products.

Search