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Malonyl Coenzyme A (lithium salt)

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    Malonyl Coenzyme A (lithium salt)
  • Malonyl Coenzyme A (lithium salt)
Cat No: 16455
Biochemicals - More Biochemicals
Cayman
€46.00
Price is excluding VAT and does not include packaging neither shipping

Malonyl coenzyme A is a coenzyme A (CoA; Item No. 16147) derivative that is used in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane.{30631,30632} Malonyl-CoA is formed by acetyl-CoA carboxy...

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • S-(hydrogen propanedioate) coenzyme A, lithium salt
Correlated keywords:
  • 524-14-1 fatty acid synthesis polyketide mitochondria lipids substrate a-ketoglutarate
Product Overview:
Malonyl coenzyme A is a coenzyme A (CoA; Item No. 16147) derivative that is used in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane.{30631,30632} Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA (Item No. 16160).{30631} Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, have been proposed to contribute to cancer cell apoptosis.{11993} Manlonyl-CoA is exclusively used as the extender unit in the synthesis of bacterial aromatic polyketides.{30632,30633}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 108347-84-8
Molecular Formula C24H38N7O19P3S • XLi
SMILES O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(O)=O)=O)=O)=O)(O)=O)(O)=O)[C@H]1OP(O)(O)=O.[Li]
Molecular Weight 860,5
Formulation A crystalline solid
Purity ≥90%
Custom Code 2930.90
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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