XPB ((Xeroderma pigmentosum group B) Monoclonal Antibody

Antibodies - Monoclonal Antibodies

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Cat No: G01069

Antibodies - Monoclonal Antibodies

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                        Territorial Availability: Available worldwide directly through Bertin or your local distributor
                    

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DNA Repair

Size	100 µL
Shipping	wet ice
Host	Mouse
Antigen	Recombinant human TFIIHp89/XPB protein.
Clone	1B3
Isotype	IgG1, ҡ
Application(s)	ELISA Western Blot Immunoprecipitation Immunocytochemistry Immunohistochemistry ChIP Recommended dilutions: 1/500-1/5000
Specificity	human TFIIHp89/XPB.
Formulation	Liquid Ascite, does not contain any preservative therefore avoid repeat freezing and thawing cycles
Custom Code	3822000000
UNSPSC code	12352203

Schaeffer L, Roy R, Humbert S, Moncollin V, Vermeulen W, Hoeijmakers JH, Chambon P, Egly JM. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science. 1993 Apr 2;260(5104):58-63

Le May N, Mota-Fernandes D, Vélez-Cruz R, Iltis I, Biard D, Egly JM. NER factors are recruited to active promoters and facilitate chromatin modification for transcription in the absence of exogenous genotoxic attack. Mol Cell. 2010. 38(1):54-66.

Alekseev S, Ayadi M, Brino L, Egly JM, Larsen AK, Coin F. A Small Molecule Screen Identifies an Inhibitor of DNA Repair Inducing the Degradation of TFIIH and the Chemosensitization of Tumor Cells to Platinum. Chem Biol. 2014 Mar 20;21(3):398-407.

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