Histone H4 acetylated Monoclonal Antibody

Antibodies - Monoclonal Antibodies

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Cat No: G01058

Antibodies - Monoclonal Antibodies

Histone H4 is a structural component of the nucleosome and is subject to covalent modification including acetylation and methylation, which may alter expression of genes located on DNA associated with its parent histone octamer.
The Histone H4 clone 3H...

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                        Territorial Availability: Available worldwide directly through Bertin or your local distributor
                    

Correlated keywords:

Epigenetics

Histone

Histone H4

Acetylated Histone

Product Overview:
Histone H4 is a structural component of the nucleosome and is subject to covalent modification including acetylation and methylation, which may alter expression of genes located on DNA associated with its parent histone octamer.
The Histone H4 clone 3HH-2C2 monoclonal recognize H4 when actelylated on at list on of the for Lysine residues K5, K8, K12 or K16.

Size	100 µL
Shipping	wet ice
Host	Mouse
Antigen	synthetic peptide: MSGRG(acetyl-K)GG(acetyl-K)GLG(acetyl-K)GGA(acetyl- K)RHRKVLR-(C) corresponding to aa 1 to 24 of human histone H4. This sequence is conserved in a wide range of species.
Clone	2C2
Isotype	IgG1, ҡ
Application(s)	ELISA Western Blot Immunoprecipitation Immunofluorescence Recommended dilutions: 1/500-1/5000
Specificity	Acetylated histone H4 at positions K5, K8, K12 or K16
Formulation	Liquid Ascite, does not contain any preservative therefore avoid repeat freezing and thawing cycles
Custom Code	3822000000
UNSPSC code	12352203

Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune F, Dilworth FJ, et al. (2001) UVdamaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. Embo J 20: 3187-3196.

Dilworth FJ, Fromental-Ramain C, Yamamoto K, Chambon P. ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro. Mol Cell. 2000. 6(5):1049-58

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