Prion Protein Monoclonal Antibody - 2G11

Antibodies - Monoclonal Antibodies

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Cat No: A03225

Antibodies - Monoclonal Antibodies

€339.00

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Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its huma...

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                        Territorial Availability: Available worldwide directly through Bertin or your local distributor
                    

Synonyms:

Prion Protein Monoclonal Antibody - 2G11

Correlated keywords:

proteins

diseases

bovine

spongiform

encephalopathy

scrapie

Creutzfeldt-jakob

neurodegeneration

antibodies

antisera

antiserum

neurochemistry

neuroscience

spi-bio

spibio

A03200

Product Overview:
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the 149-161 peptide motif on the ovine sequence that is EDRYYRENMYRYP.

Size	200 µg
Shipping	Dry Ice
Stability	Store at -20degrees;shelf life 2 years maximum after production
Host	Mouse
Antigen	This anti-Prion Protein Monoclonal Antibody was raised against a synthetic peptide (146-182) of the ovine PrP peptide.
Clone	2G11
Isotype	IgG2a
Label	Labelling upon request
Application(s)	Reconstitute the content of the vial in 1 mL of water. IHC for sheep PrPres without PK treatment For immunohistochemistry, the optimal working dilution must be determined empirically (currently between 0.1 and 1 µg/mL). Mab 2G11 binds to the partially den
Specificity	PrPres (+) Caprine, (+) Ovine, (+/-) Bovine, (+/-) Mouse, (+) Bovine Linked with 12F10, (-) Human, (-) Hamster.
Application Media	Reconstitute the content of the vial in 1 mL of water.
Formulation	lyophilized IgG with BSA
Custom Code	3822000000
UNSPSC code	12352203

Andreoletti O., Berthon P., Marc D., Sarradin P., Grosclaude J., Van Keulen L., Schelcher F., Elsen J-M., and Lantier F. (2000). Early accumulation of PrPSc in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natu

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