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13,14-dihydro-15-keto Prostaglandin D2

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    13,14-<wbr/>dihydro-<wbr/>15-<wbr/>keto Prostaglandin D<sub>2</sub>
  • 13,14-<wbr/>dihydro-<wbr/>15-<wbr/>keto Prostaglandin D<sub>2</sub>
Cat No: 12610
Biochemicals - Lipids
Cayman
€139.00
Price is excluding VAT and does not include packaging neither shipping

13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 (Item No. 12010) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/D...

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 9α-hydroxy-11,15-dioxo-prost-5Z-en-1-oic acid
Correlated keywords:
  • metabolites 13,14-dihydro-15-keto-PGD2 prostaglandins DK PGD2 diketo DKPGD2 CRTH2 DP2
Product Overview:
13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 (Item No. 12010) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor.{5248} It also inhibits ion flux in a canine colonic mucosa preparation.{9769} In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11β-hydroxy compounds which have also undergone β-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine.{418,35}
Size 1 mg
Shipping dry ice
Stability Store at -80 degrees; shelf life 365 days
CAS Number 59894-07-4
Molecular Formula C20H32O5
SMILES CCCCCC(=O)CC[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)O
Molecular Weight 352,5
Formulation A solution in methyl acetate
Purity ≥95%
Custom Code 2937.50
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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