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20-hydroxy Ecdysone

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    20-<wbr/>hydroxy Ecdysone
  • 20-<wbr/>hydroxy Ecdysone
Cat No: 16145
Biochemicals - Lipids
Cayman
€51.00
Price is excluding VAT and does not include packaging neither shipping

20-hydroxy Ecdysone is an ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis.{26314} It is also produced in plants as a defensive strategy to disrupt the dev...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • (5β)-2β,3β,14,20,22R,25-hexahydroxy-cholest-7-en-6-one
Correlated keywords:
  • 11006-​05-​6 11036-​20-​7 15266-​33-​8 15971-​08-​1 31575-​90-​3 138673-​65-​1 hormones endocrine ecdysis molting insects development metamorphosis ecdysteroids plants defense nuclear receptors ecdysone EcR cells cycles arrest growth inducible genes regulations systems transfection switch arthropods commisterone crustecdysone crustecdyson ecdysten ecdysteron ekdisten polypodin A C polypodine A C THE 7 viticosterone β-ecdysone β-ecdysterone .beta. B beta b β-ecydisone ecclysone THE-7 seven 20 E 20E 20-E THE7
Product Overview:
20-hydroxy Ecdysone is an ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis.{26314} It is also produced in plants as a defensive strategy to disrupt the development of insect pests.{26312} In target tissues, 20-hydroxy ecdysone binds to the nuclear hormone receptor, ecdysone receptor, initiating a signaling cascade that results in cell cycle arrest.{26314,26313} Ecdysteroids such as this compound have been employed as tools in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor.{26316,26315}
Size 5 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 5289-74-7
Molecular Formula C27H44O7
SMILES O=C1[C@]2([H])C[C@@H](O)[C@@H](O)C[C@]2(C)[C@]3([H])C([C@@](CC[C@]4([H])[C@]([C@H](O)CCC(C)(O)C)(O)C)(O)[C@]4(C)CC3)=C1
Molecular Weight 480,6
Formulation A crystalline solid
Purity ≥98%
Custom Code 2937.29
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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