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(±)8(9)-EpETE

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    (±)8(9)-<wbr/>EpETE
  • (±)8(9)-<wbr/>EpETE
Cat No: 10470
Biochemicals - Lipids
Cayman
€50.00
Price is excluding VAT and does not include packaging neither shipping

Eicosapentaenoic acid (EPA; Item No. 90110) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms.{18671} The major product of this epoxygenase pathway, (±)17(18)-EpETE (Item No. 50861), relaxes vascular and airway s...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • (±)8,9-epoxy-5Z,11Z,14Z,17Z-eicosatetraenoic acid
Correlated keywords:
  • eicosapentaenoic acids EPA epoxyeicosatetraenoic EpETEs EETeTr cytochromes P450 epoxygenases CYP450 (±)-8(9)-epoxy-8Z,11Z,14Z,17Z- eicosatetraenoic
Product Overview:
Eicosapentaenoic acid (EPA; Item No. 90110) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms.{18671} The major product of this epoxygenase pathway, (±)17(18)-EpETE (Item No. 50861), relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits.{9825,18669,18670} (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.{18672} The biological actions and physiological effects of this epoxide remain to be determined.
Size 25 µg
Shipping dry ice
Stability Store at -20 degrees; shelf life 365 days
CAS Number 851378-93-3
Molecular Formula C20H30O3
SMILES CC/C=C\C/C=C\C/C=C\C[C@@H](O1)[C@@H]1C/C=C\CCCC(O)=O
Molecular Weight 318,5
Formulation A solution in ethanol
Purity ≥95%
Custom Code 2910.90
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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