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Prostaglandin F

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    Prostaglandin F<sub>1α</sub>
  • Prostaglandin F<sub>1α</sub>
Cat No: 15010
Biochemicals - Lipids
Cayman
€58.00
Price is excluding VAT and does not include packaging neither shipping

PGF1? is the putative metabolite of DGLA via the COX pathway. Both PGF1? and PGF2? have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1? binds to the ovine corpus luteum FP receptor at o...

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 9α,11α,15S-trihydroxy-prost-13E-en-1-oic acid
Correlated keywords:
  • PGF1alpha PGF1.alpha. metabolites prostaglandins DGLA dihomo-.gamma.-linolenic acid dihomo-g-linolenic dihomo-gamma-linolenic COX cyclooxygenases endocrinology
Product Overview:
PGF1? is the putative metabolite of DGLA via the COX pathway. Both PGF1? and PGF2? have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1? binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2?. It is only half as active as PGF2? in inducing human respiratory smooth muscle contractions in vitro.
Prostaglandin F1? (PGF1?) is the putative metabolite of dihomo-?-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1? and PGF2? (Item Nos. 16010
10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1? binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2?. It is only half as active as PGF2? in inducing human respiratory smooth muscle contractions in vitro.
Size 1 mg
Shipping dry ice
CAS Number 745-62-0
Molecular Formula C20H36O5
SMILES O[C@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](CCCCCCC(O)=O)[C@@H](O)C1
Molecular Weight 356,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2937.50
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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